Go term | Description |
---|---|
GO:0001046 | core promoter sequence-specific DNA binding |
GO:0003677 | DNA binding |
GO:0003682 | chromatin binding |
GO:0003917 | DNA topoisomerase type I activity |
GO:0005515 | protein binding |
GO:0016853 | isomerase activity |
GO:0003916 | DNA topoisomerase activity |
Drug name | Description |
---|---|
IRINOTECAN | DNA topoisomerase I inhibitor |
Disease Name |
---|
AML* |
Gene | Organism | |
---|---|---|
TOP1 | S. cerevisiae | |
top-1 | C. elegans | |
Top1 | D. melanogaster |
Gene ID A | Gene Name A | Gene ID B | Gene Symbol B | Organism | Source | Score? | ||
---|---|---|---|---|---|---|---|---|
ENSG00000159692 | CTBP1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.975831 | View |
ENSG00000188486 | H2AFX | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.975774 | View |
ENSG00000166888 | STAT6 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.97577 | View |
ENSG00000109670 | FBXW7 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.975511 | View |
ENSG00000169375 | SIN3A | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.975314 | View |
ENSG00000096717 | SIRT1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.975048 | View |
ENSG00000183207 | RUVBL2 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974938 | View |
ENSG00000109906 | ZBTB16 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974644 | View |
ENSG00000101966 | XIAP | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974555 | View |
ENSG00000112592 | TBP | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974555 | View |
ENSG00000175792 | RUVBL1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974553 | View |
ENSG00000140992 | PDPK1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974522 | View |
ENSG00000196591 | HDAC2 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974454 | View |
ENSG00000065559 | MAP2K4 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974388 | View |
ENSG00000168148 | HIST3H3 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974373 | View |
ENSG00000103275 | UBE2I | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.974244 | View |
ENSG00000197299 | BLM | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.974176 | View |
ENSG00000100030 | MAPK1 | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.97415 | View |
ENSG00000061273 | HDAC7 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.973573 | View |
ENSG00000102882 | MAPK3 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.97349 | View |
ENSG00000100030 | MAPK1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.973178 | View |
ENSG00000060069 | CTDP1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.97294 | View |
ENSG00000116030 | SUMO1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972705 | View |
ENSG00000134057 | CCNB1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972553 | View |
ENSG00000188612 | SUMO2 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972503 | View |
ENSG00000117399 | CDC20 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972232 | View |
ENSG00000145386 | CCNA2 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972145 | View |
ENSG00000135486 | HNRNPA1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972122 | View |
ENSG00000169083 | AR | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.972102 | View |
ENSG00000164924 | YWHAZ | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.972079 | View |
ENSG00000094804 | CDC6 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971826 | View |
ENSG00000132964 | CDK8 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971824 | View |
ENSG00000143799 | PARP1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971752 | View |
ENSG00000079134 | THOC1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971752 | View |
ENSG00000100644 | HIF1A | ENSG00000198900 | TOP1 | H. sapiens | SDL | Slorth | 0.971681 | View |
ENSG00000137693 | YAP1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971676 | View |
ENSG00000169083 | AR | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971496 | View |
ENSG00000196419 | XRCC6 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971253 | View |
ENSG00000097007 | ABL1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.97125 | View |
ENSG00000116016 | EPAS1 | ENSG00000198900 | TOP1 | H. sapiens | SSL | Slorth | 0.971213 | View |