YWHAZ - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
YWHAZ	ENSG00000164924	No diseases in record	No drugs in record	protein binding transcription factor binding protein kinase binding protein domain specific binding ubiquitin protein ligase binding identical protein binding cadherin binding involved in cell-cell adhesion	BMH1 (S. cerevisiae) BMH2 (S. cerevisiae) par-5 (C. elegans) ftt-2 (C. elegans) 14-3-3zeta (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)