FBXW7 - TOP1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
FBXW7 ENSG00000109670 colorectal
endometrial
T-ALL

No drugs in record

ubiquitin-protein transferase activity
protein binding
cyclin binding
protein binding, bridging
ubiquitin protein ligase binding
identical protein binding
phosphothreonine residue binding
ubiquitin-protein transferase activator activity
MET30 (S. cerevisiae)
sel-10 (C. elegans)
ago (D. melanogaster)
TOP1 ENSG00000198900 AML*
IRINOTECAN
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
protein binding
isomerase activity
DNA topoisomerase activity
TOP1 (S. cerevisiae)
top-1 (C. elegans)
Top1 (D. melanogaster)