XRCC6 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
XRCC6	ENSG00000196419	No diseases in record	No drugs in record	DNA binding damaged DNA binding double-stranded DNA binding ATP-dependent DNA helicase activity protein binding ATP binding protein C-terminus binding transcription regulatory region DNA binding macromolecular complex binding 5'-deoxyribose-5-phosphate lyase activity double-stranded telomeric DNA binding	cku-70 (C. elegans) Irbp (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)