TOP1

ENSG00000198900 - H. sapiens

Pathways

Go term Description
GO:0001046 core promoter sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003917 DNA topoisomerase type I activity
GO:0005515 protein binding
GO:0016853 isomerase activity
GO:0003916 DNA topoisomerase activity

Drugs

Drug name Description
IRINOTECAN DNA topoisomerase I inhibitor

Diseases

Disease Name
AML*

Orthologs

Gene Organism
TOP1 S. cerevisiae
top-1 C. elegans
Top1 D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000064309 CDON ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76391 View
ENSG00000108669 CYTH1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.763836 View
ENSG00000135940 COX5B ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.763799 View
ENSG00000107295 SH3GL2 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.763641 View
ENSG00000134352 IL6ST ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.763356 View
ENSG00000138448 ITGAV ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.763283 View
ENSG00000170142 UBE2E1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76319 View
ENSG00000104980 TIMM44 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76313 View
ENSG00000049768 FOXP3 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.762905 View
ENSG00000119508 NR4A3 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.762711 View
ENSG00000136631 VPS45 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.762685 View
ENSG00000178209 PLEC ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.762507 View
ENSG00000139726 DENR ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.762257 View
ENSG00000133639 BTG1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76206 View
ENSG00000100280 AP1B1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.761934 View
ENSG00000143995 MEIS1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76188 View
ENSG00000134698 AGO4 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.761793 View
ENSG00000176884 GRIN1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.761675 View
ENSG00000140416 TPM1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.761047 View
ENSG00000131711 MAP1B ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.761046 View
ENSG00000125266 EFNB2 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.760895 View
ENSG00000128602 SMO ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.76077 View
ENSG00000104897 SF3A2 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.760294 View
ENSG00000121966 CXCR4 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.760061 View
ENSG00000129562 DAD1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.760052 View
ENSG00000108604 SMARCD2 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.760027 View
ENSG00000185359 HGS ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.759572 View
ENSG00000141378 PTRH2 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.759256 View
ENSG00000198900 TOP1 ENSG00000205339 IPO7 H. sapiens SSL Slorth 0.759045 View
ENSG00000151276 MAGI1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.759012 View
ENSG00000085733 CTTN ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.758852 View
ENSG00000149100 EIF3M ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.758826 View
ENSG00000122218 COPA ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.75858 View
ENSG00000087258 GNAO1 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.757937 View
ENSG00000101350 KIF3B ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.757913 View
ENSG00000131437 KIF3A ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.757913 View
ENSG00000165806 CASP7 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.757782 View
ENSG00000007944 MYLIP ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.757529 View
ENSG00000198286 CARD11 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.756954 View
ENSG00000162910 MRPL55 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.756209 View