TPM1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TPM1	ENSG00000140416	No diseases in record	No drugs in record	actin binding structural constituent of cytoskeleton protein binding cytoskeletal protein binding structural constituent of muscle actin filament binding actin lateral binding	lev-11 (C. elegans) Tm1 (D. melanogaster) Tm2 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)