SMO

ENSG00000128602 - H. sapiens

Pathways

Go term Description
GO:0004930 G-protein coupled receptor activity
GO:0005113 patched binding
GO:0005515 protein binding
GO:0008144 drug binding
GO:0017147 Wnt-protein binding
GO:0042813 Wnt-activated receptor activity
GO:0004888 transmembrane signaling receptor activity

Drugs

Drug name Description
VISMODEGIB Smoothened homolog inhibitor

Diseases

Disease Name
skin basal cell

Orthologs

Gene Organism
smo D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000149554 CHEK1 ENSG00000128602 SMO H. sapiens SSL BioGRID 1.0 View
ENSG00000149311 ATM ENSG00000128602 SMO H. sapiens SSL BioGRID 1.0 View
ENSG00000128602 SMO ENSG00000132646 PCNA H. sapiens SDL Slorth 0.98048 View
ENSG00000109670 FBXW7 ENSG00000128602 SMO H. sapiens SSL Slorth 0.974497 View
ENSG00000128602 SMO ENSG00000170312 CDK1 H. sapiens SDL Slorth 0.972587 View
ENSG00000128602 SMO ENSG00000177885 GRB2 H. sapiens SDL Slorth 0.972465 View
ENSG00000128602 SMO ENSG00000162385 MAGOH H. sapiens SDL Slorth 0.970435 View
ENSG00000128602 SMO ENSG00000197122 SRC H. sapiens SDL Slorth 0.969543 View
ENSG00000128602 SMO ENSG00000150991 UBC H. sapiens SDL Slorth 0.969252 View
ENSG00000128602 SMO ENSG00000169083 AR H. sapiens SDL Slorth 0.964998 View
ENSG00000128602 SMO ENSG00000133703 KRAS H. sapiens SSL Slorth 0.964894 View
ENSG00000128602 SMO ENSG00000139687 RB1 H. sapiens SDL Slorth 0.963285 View
ENSG00000128602 SMO ENSG00000146648 EGFR H. sapiens SDL Slorth 0.961983 View
ENSG00000128602 SMO ENSG00000141510 TP53 H. sapiens SDL Slorth 0.96188 View
ENSG00000128602 SMO ENSG00000168036 CTNNB1 H. sapiens SDL Slorth 0.96148 View
ENSG00000128602 SMO ENSG00000170315 UBB H. sapiens SDL Slorth 0.960161 View
ENSG00000128602 SMO ENSG00000142208 AKT1 H. sapiens SDL Slorth 0.956807 View
ENSG00000128602 SMO ENSG00000173039 RELA H. sapiens SDL Slorth 0.954979 View
ENSG00000128602 SMO ENSG00000136238 RAC1 H. sapiens SDL Slorth 0.953132 View
ENSG00000128602 SMO ENSG00000188612 SUMO2 H. sapiens SDL Slorth 0.952999 View
ENSG00000128602 SMO ENSG00000185591 SP1 H. sapiens SDL Slorth 0.952923 View
ENSG00000128602 SMO ENSG00000169375 SIN3A H. sapiens SDL Slorth 0.952461 View
ENSG00000128602 SMO ENSG00000164924 YWHAZ H. sapiens SDL Slorth 0.952366 View
ENSG00000128602 SMO ENSG00000221983 UBA52 H. sapiens SDL Slorth 0.952197 View
ENSG00000128602 SMO ENSG00000175104 TRAF6 H. sapiens SDL Slorth 0.951108 View
ENSG00000128602 SMO ENSG00000177606 JUN H. sapiens SDL Slorth 0.951071 View
ENSG00000128602 SMO ENSG00000132155 RAF1 H. sapiens SDL Slorth 0.950678 View
ENSG00000128602 SMO ENSG00000166949 SMAD3 H. sapiens SDL Slorth 0.950459 View
ENSG00000128602 SMO ENSG00000136997 MYC H. sapiens SDL Slorth 0.949893 View
ENSG00000097046 CDC7 ENSG00000128602 SMO H. sapiens SSL Slorth 0.936183 View
ENSG00000101146 RAE1 ENSG00000128602 SMO H. sapiens SSL Slorth 0.930628 View
ENSG00000128602 SMO ENSG00000174903 RAB1B H. sapiens SSL Slorth 0.928743 View
ENSG00000004700 RECQL ENSG00000128602 SMO H. sapiens SSL Slorth 0.928655 View
ENSG00000128602 SMO ENSG00000132383 RPA1 H. sapiens SDL Slorth 0.928613 View
ENSG00000128602 SMO ENSG00000138069 RAB1A H. sapiens SSL Slorth 0.917656 View
ENSG00000128602 SMO ENSG00000163960 UBXN7 H. sapiens SDL Slorth 0.912617 View
ENSG00000128602 SMO ENSG00000166913 YWHAB H. sapiens SDL Slorth 0.910195 View
ENSG00000128602 SMO ENSG00000171720 HDAC3 H. sapiens SDL Slorth 0.904146 View
ENSG00000128602 SMO ENSG00000165280 VCP H. sapiens SDL Slorth 0.901992 View
ENSG00000101868 POLA1 ENSG00000128602 SMO H. sapiens SSL Slorth 0.890085 View