ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000122966 CIT ENSG00000178568 ERBB4 H. sapiens SSL BioGRID 1.0 View
ENSG00000100393 EP300 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.989362 View
ENSG00000132646 PCNA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.988099 View
ENSG00000005339 CREBBP ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.985737 View
ENSG00000139687 RB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.9837 View
ENSG00000162385 MAGOH ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.982473 View
ENSG00000178568 ERBB4 ENSG00000213949 ITGA1 H. sapiens SDL Slorth 0.982451 View
ENSG00000136997 MYC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.981493 View
ENSG00000150991 UBC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.98144 View
ENSG00000012048 BRCA1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.980983 View
ENSG00000178568 ERBB4 ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.980855 View
ENSG00000178568 ERBB4 ENSG00000189067 LITAF H. sapiens SDL Slorth 0.980555 View
ENSG00000110395 CBL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.980509 View
ENSG00000178568 ERBB4 ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.979569 View
ENSG00000178568 ERBB4 ENSG00000206181 TCEB3B H. sapiens SDL Slorth 0.978791 View
ENSG00000178568 ERBB4 ENSG00000205629 LCMT1 H. sapiens SDL Slorth 0.977635 View
ENSG00000178568 ERBB4 ENSG00000186908 ZDHHC17 H. sapiens SDL Slorth 0.977334 View
ENSG00000116478 HDAC1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.977074 View
ENSG00000080824 HSP90AA1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.976818 View
ENSG00000178568 ERBB4 ENSG00000184470 TXNRD2 H. sapiens SDL Slorth 0.975739 View
ENSG00000142208 AKT1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.975372 View
ENSG00000141510 TP53 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.974613 View
ENSG00000146648 EGFR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.974547 View
ENSG00000072736 NFATC3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.97419 View
ENSG00000177606 JUN ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.97413 View
ENSG00000178568 ERBB4 ENSG00000182511 FES H. sapiens SDL Slorth 0.973923 View
ENSG00000178568 ERBB4 ENSG00000184012 TMPRSS2 H. sapiens SDL Slorth 0.973515 View
ENSG00000178568 ERBB4 ENSG00000182968 SOX1 H. sapiens SDL Slorth 0.97346 View
ENSG00000149554 CHEK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.973325 View
ENSG00000091831 ESR1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.97316 View
ENSG00000178568 ERBB4 ENSG00000240771 ARHGEF25 H. sapiens SDL Slorth 0.973149 View
ENSG00000178568 ERBB4 ENSG00000198838 RYR3 H. sapiens SDL Slorth 0.972462 View
ENSG00000173039 RELA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.972269 View
ENSG00000165025 SYK ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.972268 View
ENSG00000178568 ERBB4 ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.972125 View
ENSG00000135486 HNRNPA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.97199 View
ENSG00000110048 OSBP ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.971902 View
ENSG00000166913 YWHAB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.97116 View
ENSG00000067829 IDH3G ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.970973 View
ENSG00000178568 ERBB4 ENSG00000185697 MYBL1 H. sapiens SDL Slorth 0.970885 View