ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000178568 ERBB4 ENSG00000254087 LYN H. sapiens SSL Slorth 0.952541 View
ENSG00000136518 ACTL6A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95249 View
ENSG00000143799 PARP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952435 View
ENSG00000134853 PDGFRA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952403 View
ENSG00000075340 ADD2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952258 View
ENSG00000125810 CD93 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952258 View
ENSG00000067141 NEO1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952258 View
ENSG00000104738 MCM4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952241 View
ENSG00000100906 NFKBIA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952239 View
ENSG00000111262 KCNA1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952233 View
ENSG00000109971 HSPA8 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952195 View
ENSG00000115592 PRKAG3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952169 View
ENSG00000118900 UBN1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952169 View
ENSG00000125656 CLPP ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952169 View
ENSG00000171016 PYGO1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952169 View
ENSG00000154229 PRKCA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952148 View
ENSG00000136750 GAD2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.95189 View
ENSG00000099817 POLR2E ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951817 View
ENSG00000105568 PPP2R1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95172 View
ENSG00000165025 SYK ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951693 View
ENSG00000132341 RAN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951691 View
ENSG00000178568 ERBB4 ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.951353 View
ENSG00000165416 SUGT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951345 View
ENSG00000178568 ERBB4 ENSG00000181163 NPM1 H. sapiens SSL Slorth 0.951315 View
ENSG00000105810 CDK6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951297 View
ENSG00000072401 UBE2D1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.951191 View
ENSG00000124181 PLCG1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.951142 View
ENSG00000145506 NKD2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950859 View
ENSG00000096968 JAK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950795 View
ENSG00000166851 PLK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950769 View
ENSG00000174775 HRAS ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950727 View
ENSG00000147010 SH3KBP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95066 View
ENSG00000169045 HNRNPH1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950516 View
ENSG00000100387 RBX1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950433 View
ENSG00000154582 TCEB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950389 View
ENSG00000178363 CALML3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950385 View
ENSG00000166341 DCHS1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950354 View
ENSG00000087586 AURKA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950285 View
ENSG00000178568 ERBB4 ENSG00000198176 TFDP1 H. sapiens SDL Slorth 0.950214 View
ENSG00000138756 BMP2K ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.950152 View