ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000010256 UQCRC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.763391 View
ENSG00000088833 NSFL1C ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.763023 View
ENSG00000152795 HNRNPDL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762888 View
ENSG00000169251 NMD3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762752 View
ENSG00000178568 ERBB4 ENSG00000198959 TGM2 H. sapiens SSL Slorth 0.762707 View
ENSG00000111361 EIF2B1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762558 View
ENSG00000168214 RBPJ ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76248 View
ENSG00000160789 LMNA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762433 View
ENSG00000135945 REV1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762089 View
ENSG00000043093 DCUN1D1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.762072 View
ENSG00000144744 UBA3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.761681 View
ENSG00000108312 UBTF ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.761646 View
ENSG00000100804 PSMB5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.761615 View
ENSG00000083642 PDS5B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.761081 View
ENSG00000166592 RRAD ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.760789 View
ENSG00000166710 B2M ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76073 View
ENSG00000155974 GRIP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76047 View
ENSG00000134070 IRAK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.758977 View
ENSG00000131462 TUBG1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.758743 View
ENSG00000154174 TOMM70 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.758729 View
ENSG00000163902 RPN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.758632 View
ENSG00000124171 PARD6B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.757874 View
ENSG00000090861 AARS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.757716 View
ENSG00000123908 AGO2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.757354 View
ENSG00000108344 PSMD3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.757002 View
ENSG00000058262 SEC61A1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.756995 View
ENSG00000178568 ERBB4 ENSG00000185338 SOCS1 H. sapiens SSL Slorth 0.756933 View
ENSG00000154719 MRPL39 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.75677 View
ENSG00000013275 PSMC4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.75652 View
ENSG00000118058 KMT2A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.756291 View
ENSG00000160214 RRP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.756246 View
ENSG00000130522 JUND ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.755898 View
ENSG00000112335 SNX3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.755707 View
ENSG00000057608 GDI2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.755206 View
ENSG00000095139 ARCN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.754863 View
ENSG00000115677 HDLBP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.754642 View
ENSG00000113615 SEC24A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.754148 View
ENSG00000178568 ERBB4 ENSG00000196459 TRAPPC2 H. sapiens SSL Slorth 0.753872 View
ENSG00000178568 ERBB4 ENSG00000205339 IPO7 H. sapiens SSL Slorth 0.752725 View
ENSG00000125870 SNRPB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.752676 View