ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000142230 SAE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.752451 View
ENSG00000136930 PSMB7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.752402 View
ENSG00000115694 STK25 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.751461 View
ENSG00000163161 ERCC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.751389 View
ENSG00000178568 ERBB4 ENSG00000196396 PTPN1 H. sapiens SSL Slorth 0.751126 View
ENSG00000100401 RANGAP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.751105 View
ENSG00000041357 PSMA4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.751095 View
ENSG00000075413 MARK3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.750962 View
ENSG00000115317 HTRA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.750223 View
ENSG00000004975 DVL2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.750209 View
ENSG00000114126 TFDP2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.750074 View