ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000178568 ERBB4 ENSG00000184432 COPB2 H. sapiens SSL Slorth 0.775668 View
ENSG00000178184 PARD6G ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774955 View
ENSG00000104907 TRMT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774955 View
ENSG00000115866 DARS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774854 View
ENSG00000074181 NOTCH3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774633 View
ENSG00000108384 RAD51C ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774532 View
ENSG00000004660 CAMKK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.774179 View
ENSG00000070770 CSNK2A2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.773518 View
ENSG00000178568 ERBB4 ENSG00000184110 EIF3C H. sapiens SSL Slorth 0.773383 View
ENSG00000106105 GARS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.773089 View
ENSG00000178568 ERBB4 ENSG00000184260 HIST2H2AC H. sapiens SSL Slorth 0.772762 View
ENSG00000049246 PER3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.772428 View
ENSG00000077150 NFKB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.771924 View
ENSG00000155438 NIFK ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.771351 View
ENSG00000175029 CTBP2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.771142 View
ENSG00000178568 ERBB4 ENSG00000197451 HNRNPAB H. sapiens SSL Slorth 0.771084 View
ENSG00000102038 SMARCA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.771064 View
ENSG00000177426 TGIF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.77068 View
ENSG00000139197 PEX5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.770627 View
ENSG00000178568 ERBB4 ENSG00000198258 UBL5 H. sapiens SSL Slorth 0.769964 View
ENSG00000112282 MED23 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.769339 View
ENSG00000143761 ARF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.769061 View
ENSG00000276618 RAD17 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.769058 View
ENSG00000178568 ERBB4 ENSG00000215021 PHB2 H. sapiens SSL Slorth 0.768997 View
ENSG00000111596 CNOT2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.768873 View
ENSG00000108883 EFTUD2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.768849 View
ENSG00000086758 HUWE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76856 View
ENSG00000072274 TFRC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.768325 View
ENSG00000131876 SNRPA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76759 View
ENSG00000078061 ARAF ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76743 View
ENSG00000020922 MRE11 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.766363 View
ENSG00000109339 MAPK10 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.766267 View
ENSG00000163513 TGFBR2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.766033 View
ENSG00000108262 GIT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.765918 View
ENSG00000142168 SOD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.765883 View
ENSG00000136273 HUS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.765523 View
ENSG00000136279 DBNL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.764902 View
ENSG00000044115 CTNNA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.764516 View
ENSG00000096746 HNRNPH3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.76447 View
ENSG00000065000 AP3D1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.763813 View