ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000168036 CTNNB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.970852 View
ENSG00000133703 KRAS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.970617 View
ENSG00000113558 SKP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.970219 View
ENSG00000171791 BCL2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.970178 View
ENSG00000164305 CASP3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.969387 View
ENSG00000100644 HIF1A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.969332 View
ENSG00000101412 E2F1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96933 View
ENSG00000117399 CDC20 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96902 View
ENSG00000172977 KAT5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968589 View
ENSG00000139687 RB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96857 View
ENSG00000130726 TRIM28 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968555 View
ENSG00000121774 KHDRBS1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.968433 View
ENSG00000135446 CDK4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968237 View
ENSG00000096717 SIRT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968199 View
ENSG00000116030 SUMO1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968109 View
ENSG00000103275 UBE2I ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968063 View
ENSG00000149311 ATM ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968036 View
ENSG00000112062 MAPK14 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968027 View
ENSG00000166167 BTRC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.968008 View
ENSG00000134086 VHL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.967988 View
ENSG00000175792 RUVBL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.967589 View
ENSG00000112592 TBP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.967571 View
ENSG00000104140 RHOV ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.967539 View
ENSG00000168148 HIST3H3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.967467 View
ENSG00000141027 NCOR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.967188 View
ENSG00000178568 ERBB4 ENSG00000197299 BLM H. sapiens SSL Slorth 0.9671 View
ENSG00000166949 SMAD3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.967032 View
ENSG00000101365 IDH3B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.966989 View
ENSG00000101266 CSNK2A1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.966986 View
ENSG00000101266 CSNK2A1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.966923 View
ENSG00000121022 COPS5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.966641 View
ENSG00000010810 FYN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.966502 View
ENSG00000136238 RAC1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.966198 View
ENSG00000169083 AR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.96597 View
ENSG00000079156 OSBPL6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.965772 View
ENSG00000135018 UBQLN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965762 View
ENSG00000165125 TRPV6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.965737 View
ENSG00000178568 ERBB4 ENSG00000183791 TCEB3C H. sapiens SDL Slorth 0.965671 View
ENSG00000094804 CDC6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965627 View
ENSG00000163485 ADORA1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.965565 View