ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000080815 PSEN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.957349 View
ENSG00000141503 MINK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.957273 View
ENSG00000166913 YWHAB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.957266 View
ENSG00000021574 SPAST ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.957254 View
ENSG00000097007 ABL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.957215 View
ENSG00000178568 ERBB4 ENSG00000188906 LRRK2 H. sapiens SSL Slorth 0.957005 View
ENSG00000126261 UBA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956851 View
ENSG00000169220 RGS14 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.956834 View
ENSG00000104365 IKBKB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956769 View
ENSG00000167986 DDB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956707 View
ENSG00000138376 BARD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956554 View
ENSG00000137942 FNBP1L ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.956436 View
ENSG00000102317 RBM3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.956406 View
ENSG00000114423 CBLB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.956405 View
ENSG00000124762 CDKN1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956224 View
ENSG00000121879 PIK3CA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956219 View
ENSG00000178568 ERBB4 ENSG00000187555 USP7 H. sapiens SSL Slorth 0.956217 View
ENSG00000117400 MPL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.956155 View
ENSG00000089159 PXN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956051 View
ENSG00000162231 NXF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.956013 View
ENSG00000171634 BPTF ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955894 View
ENSG00000005882 PDK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955887 View
ENSG00000117748 RPA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955878 View
ENSG00000106346 USP42 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955795 View
ENSG00000114166 KAT2B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95578 View
ENSG00000103126 AXIN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955751 View
ENSG00000170162 VGLL2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.95572 View
ENSG00000079335 CDC14A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.9556 View
ENSG00000100320 RBFOX2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955486 View
ENSG00000077279 DCX ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955451 View
ENSG00000140199 SLC12A6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955363 View
ENSG00000149136 SSRP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955312 View
ENSG00000173039 RELA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955269 View
ENSG00000142192 APP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955163 View
ENSG00000154997 SEPT14 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.95514 View
ENSG00000005007 UPF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955028 View
ENSG00000110031 LPXN ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.955017 View
ENSG00000108424 KPNB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.955009 View
ENSG00000100982 PCIF1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954897 View
ENSG00000077935 SMC1B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954885 View