ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000177885 GRB2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954862 View
ENSG00000178568 ERBB4 ENSG00000198793 MTOR H. sapiens SDL Slorth 0.954861 View
ENSG00000164144 ARFIP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954828 View
ENSG00000134308 YWHAQ ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95465 View
ENSG00000157601 MX1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954628 View
ENSG00000117676 RPS6KA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954575 View
ENSG00000148248 SURF4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954558 View
ENSG00000099785 MARCH2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954558 View
ENSG00000072518 MARK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954543 View
ENSG00000169139 UBE2V2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954477 View
ENSG00000176894 PXMP2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954431 View
ENSG00000130703 OSBPL2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954425 View
ENSG00000152601 MBNL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.954373 View
ENSG00000150093 ITGB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954278 View
ENSG00000109332 UBE2D3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954231 View
ENSG00000178568 ERBB4 ENSG00000182866 LCK H. sapiens SSL Slorth 0.954143 View
ENSG00000160691 SHC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.954121 View
ENSG00000146830 GIGYF1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953939 View
ENSG00000148200 NR6A1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953906 View
ENSG00000047315 POLR2B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.953893 View
ENSG00000178568 ERBB4 ENSG00000184675 AMER1 H. sapiens SDL Slorth 0.953854 View
ENSG00000178568 ERBB4 ENSG00000188130 MAPK12 H. sapiens SDL Slorth 0.953844 View
ENSG00000178568 ERBB4 ENSG00000181788 SIAH2 H. sapiens SDL Slorth 0.953815 View
ENSG00000127329 PTPRB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953591 View
ENSG00000138829 FBN2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953591 View
ENSG00000062822 POLD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95359 View
ENSG00000058729 RIOK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.953563 View
ENSG00000136014 USP44 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953513 View
ENSG00000178568 ERBB4 ENSG00000196591 HDAC2 H. sapiens SSL Slorth 0.953305 View
ENSG00000114062 UBE3A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.953191 View
ENSG00000169750 RAC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.953179 View
ENSG00000111049 MYF5 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953147 View
ENSG00000120539 MASTL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953098 View
ENSG00000112679 DUSP22 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.953055 View
ENSG00000089159 PXN ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952933 View
ENSG00000164109 MAD2L1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.952918 View
ENSG00000129354 AP1M2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952826 View
ENSG00000115221 ITGB6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952796 View
ENSG00000165409 TSHR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.952758 View
ENSG00000066455 GOLGA5 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.95268 View