ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000041353 RAB27B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948146 View
ENSG00000079134 THOC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948143 View
ENSG00000166508 MCM7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948126 View
ENSG00000178568 ERBB4 ENSG00000181163 NPM1 H. sapiens SDL Slorth 0.947977 View
ENSG00000115507 OTX1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947782 View
ENSG00000070718 AP3M2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947744 View
ENSG00000102781 KATNAL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947688 View
ENSG00000178568 ERBB4 ENSG00000244687 UBE2V1 H. sapiens SSL Slorth 0.947683 View
ENSG00000090889 KIF4A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947623 View
ENSG00000131747 TOP2A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947604 View
ENSG00000134138 MEIS2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947592 View
ENSG00000100239 PPP6R2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947551 View
ENSG00000074219 TEAD2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947509 View
ENSG00000110092 CCND1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947495 View
ENSG00000178568 ERBB4 ENSG00000188486 H2AFX H. sapiens SSL Slorth 0.947474 View
ENSG00000115216 NRBP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947224 View
ENSG00000164056 SPRY1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947202 View
ENSG00000178568 ERBB4 ENSG00000184634 MED12 H. sapiens SSL Slorth 0.94719 View
ENSG00000082146 STRADB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94718 View
ENSG00000163435 ELF3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947168 View
ENSG00000136238 RAC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947164 View
ENSG00000101665 SMAD7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947157 View
ENSG00000104695 PPP2CB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947143 View
ENSG00000063244 U2AF2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.947108 View
ENSG00000145734 BDP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.947018 View
ENSG00000126785 RHOJ ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946955 View
ENSG00000151692 RNF144A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946927 View
ENSG00000178568 ERBB4 ENSG00000188612 SUMO2 H. sapiens SSL Slorth 0.946821 View
ENSG00000164284 GRPEL2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946689 View
ENSG00000154473 BUB3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946673 View
ENSG00000106327 TFR2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946651 View
ENSG00000135597 REPS1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946613 View
ENSG00000177889 UBE2N ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946588 View
ENSG00000167550 RHEBL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946544 View
ENSG00000165527 ARF6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946454 View
ENSG00000105173 CCNE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946439 View
ENSG00000178568 ERBB4 ENSG00000185386 MAPK11 H. sapiens SDL Slorth 0.94643 View
ENSG00000112118 MCM3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946383 View
ENSG00000110395 CBL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946356 View
ENSG00000010810 FYN ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946272 View