ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000178568 ERBB4 ENSG00000182255 KCNA4 H. sapiens SDL Slorth 0.94348 View
ENSG00000087274 ADD1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94347 View
ENSG00000159352 PSMD4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.943359 View
ENSG00000138069 RAB1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943354 View
ENSG00000176170 SPHK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.943347 View
ENSG00000166888 STAT6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943284 View
ENSG00000166228 PCBD1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.943205 View
ENSG00000140464 PML ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943044 View
ENSG00000113558 SKP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943028 View
ENSG00000084774 CAD ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.943015 View
ENSG00000146232 NFKBIE ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942973 View
ENSG00000102978 POLR2C ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.942897 View
ENSG00000145604 SKP2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.942882 View
ENSG00000105568 PPP2R1A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942725 View
ENSG00000153147 SMARCA5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.942548 View
ENSG00000141646 SMAD4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942499 View
ENSG00000133101 CCNA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.942391 View
ENSG00000137825 ITPKA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942257 View
ENSG00000163098 BIRC8 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942202 View
ENSG00000143847 PPFIA4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.942173 View
ENSG00000127586 CHTF18 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.941994 View
ENSG00000118260 CREB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.94199 View
ENSG00000151746 BICD1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94195 View
ENSG00000136875 PRPF4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.941894 View
ENSG00000132437 DDC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941748 View
ENSG00000129559 NEDD8 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.941725 View
ENSG00000145358 DDIT4L ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941672 View
ENSG00000178568 ERBB4 ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.941582 View
ENSG00000170624 SGCD ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941533 View
ENSG00000170315 UBB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941527 View
ENSG00000058404 CAMK2B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941458 View
ENSG00000156345 CDK20 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941426 View
ENSG00000066923 STAG3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941324 View
ENSG00000178568 ERBB4 ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.94127 View
ENSG00000170836 PPM1D ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941234 View
ENSG00000165819 METTL3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.941017 View
ENSG00000093009 CDC45 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.940931 View
ENSG00000143190 POU2F1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.94092 View
ENSG00000123200 ZC3H13 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.940913 View
ENSG00000080503 SMARCA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.940896 View