PPM1D - ERBB4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PPM1D	ENSG00000170836	glioma ovarian cancer breast cancer	No drugs in record	protein serine/threonine phosphatase activity protein binding metal ion binding mitogen-activated protein kinase binding	PTC2 (S. cerevisiae) PTC3 (S. cerevisiae)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)