ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000075785 RAB7A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.933289 View
ENSG00000120500 ARR3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933282 View
ENSG00000124782 RREB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933172 View
ENSG00000143344 RGL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933167 View
ENSG00000148840 PPRC1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933154 View
ENSG00000061938 TNK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.933098 View
ENSG00000160360 GPSM1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933077 View
ENSG00000170312 CDK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.933012 View
ENSG00000023445 BIRC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.932991 View
ENSG00000141736 ERBB2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932894 View
ENSG00000122592 HOXA7 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932815 View
ENSG00000106462 EZH2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.93264 View
ENSG00000152578 GRIA4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932625 View
ENSG00000080224 EPHA6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932582 View
ENSG00000147647 DPYS ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932513 View
ENSG00000144644 GADL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.932513 View
ENSG00000131508 UBE2D2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.932474 View
ENSG00000084676 NCOA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.932318 View
ENSG00000112531 QKI ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.931981 View
ENSG00000178568 ERBB4 ENSG00000198742 SMURF1 H. sapiens SSL Slorth 0.931889 View
ENSG00000134086 VHL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931873 View
ENSG00000143355 LHX9 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931744 View
ENSG00000137166 FOXP4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931744 View
ENSG00000178568 ERBB4 ENSG00000204389 HSPA1A H. sapiens SDL Slorth 0.931653 View
ENSG00000178568 ERBB4 ENSG00000204390 HSPA1L H. sapiens SDL Slorth 0.931653 View
ENSG00000077092 RARB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931648 View
ENSG00000004897 CDC27 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931591 View
ENSG00000101412 E2F1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.93153 View
ENSG00000101213 PTK6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931511 View
ENSG00000100644 HIF1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.931454 View
ENSG00000172367 PDZD3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.93128 View
ENSG00000092421 SEMA6A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.93123 View
ENSG00000117707 PROX1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931211 View
ENSG00000173404 INSM1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.931181 View
ENSG00000053900 ANAPC4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.931115 View
ENSG00000108840 HDAC5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.931065 View
ENSG00000178568 ERBB4 ENSG00000198825 INPP5F H. sapiens SDL Slorth 0.931006 View
ENSG00000154237 LRRK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.930996 View
ENSG00000158092 NCK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.930842 View
ENSG00000163536 SERPINI1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.930824 View