ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000178568 ERBB4 ENSG00000244687 UBE2V1 H. sapiens SDL Slorth 0.918557 View
ENSG00000175390 EIF3F ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.91845 View
ENSG00000178568 ERBB4 ENSG00000244405 ETV5 H. sapiens SDL Slorth 0.918128 View
ENSG00000178568 ERBB4 ENSG00000198876 DCAF12 H. sapiens SDL Slorth 0.918125 View
ENSG00000168542 COL3A1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.918056 View
ENSG00000105974 CAV1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917884 View
ENSG00000165115 KIF27 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.917877 View
ENSG00000164032 H2AFZ ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917757 View
ENSG00000165731 RET ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917651 View
ENSG00000134001 EIF2S1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917606 View
ENSG00000150459 SAP18 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917569 View
ENSG00000010017 RANBP9 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.917553 View
ENSG00000175354 PTPN2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.917298 View
ENSG00000178568 ERBB4 ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.917193 View
ENSG00000082701 GSK3B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.916987 View
ENSG00000134982 APC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.916763 View
ENSG00000134363 FST ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.916756 View
ENSG00000101134 DOK5 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.916696 View
ENSG00000131941 RHPN2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.916471 View
ENSG00000120656 TAF12 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.916457 View
ENSG00000130177 CDC16 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.91633 View
ENSG00000120438 TCP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.916217 View
ENSG00000123405 NFE2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.91616 View
ENSG00000178568 ERBB4 ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.91616 View
ENSG00000178568 ERBB4 ENSG00000198668 CALM1 H. sapiens SDL Slorth 0.916134 View
ENSG00000178568 ERBB4 ENSG00000197157 SND1 H. sapiens SDL Slorth 0.915948 View
ENSG00000157404 KIT ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.915811 View
ENSG00000168090 COPS6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.915772 View
ENSG00000178568 ERBB4 ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.915742 View
ENSG00000129152 MYOD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.915187 View
ENSG00000178568 ERBB4 ENSG00000198087 CD2AP H. sapiens SDL Slorth 0.91513 View
ENSG00000141367 CLTC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.915032 View
ENSG00000178568 ERBB4 ENSG00000183454 GRIN2A H. sapiens SDL Slorth 0.914897 View
ENSG00000178568 ERBB4 ENSG00000185651 UBE2L3 H. sapiens SSL Slorth 0.914626 View
ENSG00000130985 UBA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.914513 View
ENSG00000148400 NOTCH1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.914483 View
ENSG00000124232 RBPJL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.914384 View
ENSG00000159263 SIM2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.914245 View
ENSG00000178568 ERBB4 ENSG00000178573 MAF H. sapiens SDL Slorth 0.914199 View
ENSG00000130751 NPAS1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.914188 View