ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000085511 MAP3K4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.900863 View
ENSG00000035403 VCL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.900734 View
ENSG00000037280 FLT4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.900597 View
ENSG00000111276 CDKN1B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.90049 View
ENSG00000178568 ERBB4 ENSG00000220205 VAMP2 H. sapiens SDL Slorth 0.900488 View
ENSG00000178568 ERBB4 ENSG00000196396 PTPN1 H. sapiens SDL Slorth 0.900395 View
ENSG00000178568 ERBB4 ENSG00000196218 RYR1 H. sapiens SDL Slorth 0.900337 View
ENSG00000178568 ERBB4 ENSG00000188021 UBQLN2 H. sapiens SSL Slorth 0.899665 View
ENSG00000164362 TERT ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.899665 View
ENSG00000167491 GATAD2A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.899532 View
ENSG00000178568 ERBB4 ENSG00000185787 MORF4L1 H. sapiens SSL Slorth 0.898641 View
ENSG00000141552 ANAPC11 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.898627 View
ENSG00000153250 RBMS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.898334 View
ENSG00000158092 NCK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.898309 View
ENSG00000106211 HSPB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.898191 View
ENSG00000106245 BUD31 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.897581 View
ENSG00000178568 ERBB4 ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.897157 View
ENSG00000140396 NCOA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.895988 View
ENSG00000109062 SLC9A3R1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.895524 View
ENSG00000152818 UTRN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.895486 View
ENSG00000076555 ACACB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.895381 View
ENSG00000166333 ILK ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.894278 View
ENSG00000117133 RPF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.893118 View
ENSG00000079102 RUNX1T1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.892076 View
ENSG00000168438 CDC40 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.891682 View
ENSG00000178568 ERBB4 ENSG00000186716 BCR H. sapiens SSL Slorth 0.890871 View
ENSG00000178568 ERBB4 ENSG00000198668 CALM1 H. sapiens SSL Slorth 0.890736 View
ENSG00000072110 ACTN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.890618 View
ENSG00000171720 HDAC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.890502 View
ENSG00000136937 NCBP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889856 View
ENSG00000145715 RASA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889813 View
ENSG00000178568 ERBB4 ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.889528 View
ENSG00000088986 DYNLL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889523 View
ENSG00000087095 NLK ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889382 View
ENSG00000094916 CBX5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889272 View
ENSG00000128591 FLNC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.889242 View
ENSG00000178568 ERBB4 ENSG00000181788 SIAH2 H. sapiens SSL Slorth 0.888351 View
ENSG00000132326 PER2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.888274 View
ENSG00000117713 ARID1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.888062 View
ENSG00000144566 RAB5A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.887794 View