ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000039068 CDH1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.910246 View
ENSG00000071051 NCK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.910188 View
ENSG00000171105 INSR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.91009 View
ENSG00000115904 SOS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.909988 View
ENSG00000114867 EIF4G1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.909963 View
ENSG00000026103 FAS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.909897 View
ENSG00000101665 SMAD7 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.909794 View
ENSG00000116478 HDAC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.909621 View
ENSG00000109971 HSPA8 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.909419 View
ENSG00000118503 TNFAIP3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.908912 View
ENSG00000131759 RARA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.908795 View
ENSG00000178568 ERBB4 ENSG00000248905 FMN1 H. sapiens SDL Slorth 0.908702 View
ENSG00000149923 PPP4C ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.908699 View
ENSG00000087586 AURKA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.9086 View
ENSG00000080824 HSP90AA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.908161 View
ENSG00000106299 WASL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.90796 View
ENSG00000169047 IRS1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.907953 View
ENSG00000063438 AHRR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.907825 View
ENSG00000130332 LSM7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.907807 View
ENSG00000108947 EFNB3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.907635 View
ENSG00000051382 PIK3CB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.907535 View
ENSG00000004487 KDM1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.907393 View
ENSG00000178568 ERBB4 ENSG00000180370 PAK2 H. sapiens SSL Slorth 0.907366 View
ENSG00000178568 ERBB4 ENSG00000221978 CCNL2 H. sapiens SDL Slorth 0.907366 View
ENSG00000143420 ENSA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.907287 View
ENSG00000178568 ERBB4 ENSG00000182578 CSF1R H. sapiens SDL Slorth 0.907262 View
ENSG00000167986 DDB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.906769 View
ENSG00000126457 PRMT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.906605 View
ENSG00000124813 RUNX2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905846 View
ENSG00000135144 DTX1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.905782 View
ENSG00000177084 POLE ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905752 View
ENSG00000166200 COPS2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905683 View
ENSG00000130699 TAF4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905604 View
ENSG00000162236 STX5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.90556 View
ENSG00000178568 ERBB4 ENSG00000186575 NF2 H. sapiens SSL Slorth 0.90551 View
ENSG00000149930 TAOK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.905499 View
ENSG00000001167 NFYA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905422 View
ENSG00000178568 ERBB4 ENSG00000198400 NTRK1 H. sapiens SDL Slorth 0.905324 View
ENSG00000076242 MLH1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905255 View
ENSG00000156052 GNAQ ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.905198 View