ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000147065 MSN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.887332 View
ENSG00000110713 NUP98 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.887196 View
ENSG00000177169 ULK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884996 View
ENSG00000111424 VDR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884842 View
ENSG00000110107 PRPF19 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884763 View
ENSG00000105976 MET ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884571 View
ENSG00000092108 SCFD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884189 View
ENSG00000122512 PMS2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.884058 View
ENSG00000173473 SMARCC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.88398 View
ENSG00000138668 HNRNPD ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.883561 View
ENSG00000070756 PABPC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.883527 View
ENSG00000136100 VPS36 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.883451 View
ENSG00000168036 CTNNB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881976 View
ENSG00000165392 WRN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881611 View
ENSG00000170606 HSPA4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881554 View
ENSG00000178568 ERBB4 ENSG00000185104 FAF1 H. sapiens SSL Slorth 0.881449 View
ENSG00000047249 ATP6V1H ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881199 View
ENSG00000069329 VPS35 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881082 View
ENSG00000166598 HSP90B1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.880159 View
ENSG00000135521 LTV1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.879721 View
ENSG00000068078 FGFR3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.879623 View
ENSG00000074266 EED ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.879108 View
ENSG00000132906 CASP9 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877908 View
ENSG00000167461 RAB8A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877453 View
ENSG00000178568 ERBB4 ENSG00000198911 SREBF2 H. sapiens SSL Slorth 0.877431 View
ENSG00000156970 BUB1B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877333 View
ENSG00000139343 SNRPF ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877301 View
ENSG00000119718 EIF2B2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877193 View
ENSG00000144848 ATG3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877097 View
ENSG00000118689 FOXO3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.877008 View
ENSG00000101161 PRPF6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876882 View
ENSG00000116350 SRSF4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876743 View
ENSG00000130826 DKC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876724 View
ENSG00000104852 SNRNP70 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876629 View
ENSG00000062650 WAPL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876379 View
ENSG00000162367 TAL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876297 View
ENSG00000172534 HCFC1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876075 View
ENSG00000170315 UBB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.876002 View
ENSG00000119335 SET ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.875754 View
ENSG00000170144 HNRNPA3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.874937 View