ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000115524 SF3B1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.864199 View
ENSG00000113812 ACTR8 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.863743 View
ENSG00000128052 KDR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.863255 View
ENSG00000156603 MED19 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.863125 View
ENSG00000112658 SRF ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.862553 View
ENSG00000116039 ATP6V1B1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.862484 View
ENSG00000113013 HSPA9 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.861097 View
ENSG00000133119 RFC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.860636 View
ENSG00000075711 DLG1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.860311 View
ENSG00000171824 EXOSC10 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.860101 View
ENSG00000163466 ARPC2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.860052 View
ENSG00000085733 CTTN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859527 View
ENSG00000151090 THRB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859403 View
ENSG00000166266 CUL5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859336 View
ENSG00000108055 SMC3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859285 View
ENSG00000172115 CYCS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859054 View
ENSG00000151532 VTI1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.859002 View
ENSG00000129083 COPB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85855 View
ENSG00000077097 TOP2B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85822 View
ENSG00000130725 UBE2M ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.858147 View
ENSG00000172409 CLP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85772 View
ENSG00000047932 GOPC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.857702 View
ENSG00000178568 ERBB4 ENSG00000179218 CALR H. sapiens SSL Slorth 0.857269 View
ENSG00000100028 SNRPD3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85723 View
ENSG00000092531 SNAP23 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.856741 View
ENSG00000122565 CBX3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.856546 View
ENSG00000106070 GRB10 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.856255 View
ENSG00000122257 RBBP6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.856193 View
ENSG00000159216 RUNX1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.855987 View
ENSG00000049618 ARID1B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85597 View
ENSG00000065427 KARS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.855933 View
ENSG00000074211 PPP2R2C ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.855407 View
ENSG00000101343 CRNKL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.855092 View
ENSG00000088832 FKBP1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.854904 View
ENSG00000169252 ADRB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.853964 View
ENSG00000163041 H3F3A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.853665 View
ENSG00000150995 ITPR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.85355 View
ENSG00000100201 DDX17 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.853488 View
ENSG00000171843 MLLT3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.853478 View
ENSG00000178568 ERBB4 ENSG00000238134 EHMT2 H. sapiens SSL Slorth 0.853406 View