ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000029639 TFB1M ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.92664 View
ENSG00000166167 BTRC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.926504 View
ENSG00000064012 CASP8 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.926254 View
ENSG00000178568 ERBB4 ENSG00000198561 CTNND1 H. sapiens SSL Slorth 0.926186 View
ENSG00000077721 UBE2A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.926126 View
ENSG00000147010 SH3KBP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.926039 View
ENSG00000159461 AMFR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.926016 View
ENSG00000172732 MUS81 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925915 View
ENSG00000048462 TNFRSF17 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.925801 View
ENSG00000006451 RALA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925774 View
ENSG00000169282 KCNAB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.925497 View
ENSG00000039068 CDH1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925432 View
ENSG00000178568 ERBB4 ENSG00000204209 DAXX H. sapiens SDL Slorth 0.925421 View
ENSG00000073584 SMARCE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925353 View
ENSG00000117625 RCOR3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.925254 View
ENSG00000096384 HSP90AB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925252 View
ENSG00000130939 UBE4B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925172 View
ENSG00000136807 CDK9 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.925163 View
ENSG00000011454 RABGAP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.925161 View
ENSG00000169435 RASSF6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.925021 View
ENSG00000101349 PAK5 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.924829 View
ENSG00000175595 ERCC4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.92476 View
ENSG00000149269 PAK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.924723 View
ENSG00000127445 PIN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.924614 View
ENSG00000079432 CIC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.924477 View
ENSG00000170345 FOS ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.924326 View
ENSG00000107581 EIF3A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.924321 View
ENSG00000163558 PRKCI ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.924081 View
ENSG00000178568 ERBB4 ENSG00000198625 MDM4 H. sapiens SDL Slorth 0.923868 View
ENSG00000135446 CDK4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.923837 View
ENSG00000178568 ERBB4 ENSG00000178999 AURKB H. sapiens SSL Slorth 0.923775 View
ENSG00000106290 TAF6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.923559 View
ENSG00000139631 CSAD ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.923521 View
ENSG00000175518 UBQLNL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.923521 View
ENSG00000080986 NDC80 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.923519 View
ENSG00000106263 EIF3B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.923392 View
ENSG00000137693 YAP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.923285 View
ENSG00000168496 FEN1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.923207 View
ENSG00000178568 ERBB4 ENSG00000198400 NTRK1 H. sapiens SSL Slorth 0.923172 View
ENSG00000157216 SSBP3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.923149 View