ERCC4 - ERBB4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERCC4	ENSG00000175595	skin basal cell skin squamous cell melanoma	No drugs in record	single-stranded DNA endodeoxyribonuclease activity TFIID-class transcription factor binding damaged DNA binding single-stranded DNA binding endodeoxyribonuclease activity protein binding protein C-terminus binding protein N-terminus binding	RAD1 (S. cerevisiae) xpf-1 (C. elegans) mei-9 (D. melanogaster)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)