ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000149781 FERMT3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938836 View
ENSG00000092201 SUPT16H ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938745 View
ENSG00000070831 CDC42 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938739 View
ENSG00000178568 ERBB4 ENSG00000185022 MAFF H. sapiens SDL Slorth 0.938738 View
ENSG00000170365 SMAD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938678 View
ENSG00000178568 ERBB4 ENSG00000204435 CSNK2B H. sapiens SDL Slorth 0.938667 View
ENSG00000154229 PRKCA ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938642 View
ENSG00000105287 PRKD2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938617 View
ENSG00000177885 GRB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.93854 View
ENSG00000166501 PRKCB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938539 View
ENSG00000178568 ERBB4 ENSG00000205726 ITSN1 H. sapiens SDL Slorth 0.938374 View
ENSG00000096717 SIRT1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938368 View
ENSG00000143257 NR1I3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938363 View
ENSG00000108094 CUL2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938342 View
ENSG00000134871 COL4A2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938314 View
ENSG00000165055 METTL2B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938292 View
ENSG00000087995 METTL2A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938292 View
ENSG00000140750 ARHGAP17 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938241 View
ENSG00000169862 CTNND2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.93824 View
ENSG00000077097 TOP2B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938192 View
ENSG00000104892 KLC3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938188 View
ENSG00000138594 TMOD3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938124 View
ENSG00000100228 RAB36 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938124 View
ENSG00000085185 BCORL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.938124 View
ENSG00000085832 EPS15 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938116 View
ENSG00000167513 CDT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.938071 View
ENSG00000070404 FSTL3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937971 View
ENSG00000125740 FOSB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937934 View
ENSG00000168610 STAT3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937652 View
ENSG00000113456 RAD1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937605 View
ENSG00000044574 HSPA5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937592 View
ENSG00000051180 RAD51 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937518 View
ENSG00000100906 NFKBIA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937409 View
ENSG00000165238 WNK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937382 View
ENSG00000118046 STK11 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937374 View
ENSG00000175387 SMAD2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937302 View
ENSG00000174567 GOLT1A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937199 View
ENSG00000165832 TRUB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.937166 View
ENSG00000146648 EGFR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937122 View
ENSG00000114423 CBLB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.937018 View