ERBB4 - ITSN1

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)
ITSN1	ENSG00000205726	No diseases in record	No drugs in record	guanyl-nucleotide exchange factor activity Rho guanyl-nucleotide exchange factor activity calcium ion binding protein binding kinase activator activity protein complex scaffold activity proline-rich region binding	EDE1 (S. cerevisiae) Dap160 (D. melanogaster)