ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000137486 ARRB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946212 View
ENSG00000132964 CDK8 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.946211 View
ENSG00000161940 BCL6B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946158 View
ENSG00000148730 EIF4EBP2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.946066 View
ENSG00000115616 SLC9A2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945929 View
ENSG00000137845 ADAM10 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945708 View
ENSG00000178568 ERBB4 ENSG00000178997 EXD1 H. sapiens SDL Slorth 0.945678 View
ENSG00000178568 ERBB4 ENSG00000214102 WEE2 H. sapiens SDL Slorth 0.945654 View
ENSG00000146701 MDH2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945595 View
ENSG00000163517 HDAC11 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945432 View
ENSG00000146094 DOK3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945387 View
ENSG00000091831 ESR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.945342 View
ENSG00000085999 RAD54L ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945233 View
ENSG00000096968 JAK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.945217 View
ENSG00000178568 ERBB4 ENSG00000198793 MTOR H. sapiens SSL Slorth 0.945199 View
ENSG00000101966 XIAP ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945165 View
ENSG00000143252 SDHC ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945114 View
ENSG00000113240 CLK4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.945109 View
ENSG00000060069 CTDP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.945067 View
ENSG00000123600 METTL8 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944878 View
ENSG00000121481 RNF2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944852 View
ENSG00000108443 RPS6KB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944827 View
ENSG00000178568 ERBB4 ENSG00000221829 FANCG H. sapiens SDL Slorth 0.944822 View
ENSG00000123612 ACVR1C ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944749 View
ENSG00000140464 PML ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944703 View
ENSG00000171791 BCL2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94468 View
ENSG00000166947 EPB42 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944538 View
ENSG00000176208 ATAD5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944355 View
ENSG00000055332 EIF2AK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944283 View
ENSG00000134982 APC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944137 View
ENSG00000164885 CDK5 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944112 View
ENSG00000079337 RAPGEF3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944104 View
ENSG00000153922 CHD1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.944063 View
ENSG00000067560 RHOA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.944032 View
ENSG00000178568 ERBB4 ENSG00000198561 CTNND1 H. sapiens SDL Slorth 0.943938 View
ENSG00000147133 TAF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943701 View
ENSG00000135624 CCT7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943681 View
ENSG00000162434 JAK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943662 View
ENSG00000163932 PRKCD ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.943612 View
ENSG00000078114 NEBL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94349 View