ADAM10 - ERBB4

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ADAM10	ENSG00000137845	No diseases in record	No drugs in record	endopeptidase activity metalloendopeptidase activity receptor binding integrin binding protein binding metallopeptidase activity SH3 domain binding protein kinase binding protein homodimerization activity metal ion binding	sup-17 (C. elegans)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)