CDK8 - ERBB4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CDK8	ENSG00000132964	No diseases in record	No drugs in record	protein kinase activity protein serine/threonine kinase activity cyclin-dependent protein serine/threonine kinase activity protein binding ATP binding RNA polymerase II carboxy-terminal domain kinase activity RNA polymerase II transcription cofactor activity	SSN3 (S. cerevisiae) cdk-8 (C. elegans) Cdk8 (D. melanogaster)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)