ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000001626 CFTR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.950043 View
ENSG00000110330 BIRC2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949967 View
ENSG00000075624 ACTB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949943 View
ENSG00000111875 ASF1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949892 View
ENSG00000178568 ERBB4 ENSG00000185513 L3MBTL1 H. sapiens SDL Slorth 0.949814 View
ENSG00000049323 LTBP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.949786 View
ENSG00000178568 ERBB4 ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.94973 View
ENSG00000157106 SMG1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949613 View
ENSG00000132466 ANKRD17 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.94958 View
ENSG00000167552 TUBA1A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949567 View
ENSG00000175054 ATR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949476 View
ENSG00000141564 RPTOR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949391 View
ENSG00000178568 ERBB4 ENSG00000198900 TOP1 H. sapiens SSL Slorth 0.949354 View
ENSG00000172296 SPTLC3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.949144 View
ENSG00000036257 CUL3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949143 View
ENSG00000128245 YWHAH ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.949088 View
ENSG00000099365 STX1B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.949066 View
ENSG00000078140 UBE2K ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.949044 View
ENSG00000086619 ERO1B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.949026 View
ENSG00000072422 RHOBTB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948967 View
ENSG00000008853 RHOBTB2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948967 View
ENSG00000132646 PCNA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948961 View
ENSG00000079999 KEAP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948857 View
ENSG00000006468 ETV1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948764 View
ENSG00000148677 ANKRD1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948758 View
ENSG00000151150 ANK3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948663 View
ENSG00000128271 ADORA2A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948654 View
ENSG00000168487 BMP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948654 View
ENSG00000178568 ERBB4 ENSG00000204103 MAFB H. sapiens SDL Slorth 0.948643 View
ENSG00000171126 KCNG3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948628 View
ENSG00000165280 VCP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948621 View
ENSG00000125967 NECAB3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948559 View
ENSG00000061918 GUCY1B3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948559 View
ENSG00000139998 RAB15 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948559 View
ENSG00000078747 ITCH ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948501 View
ENSG00000112062 MAPK14 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948452 View
ENSG00000099956 SMARCB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.94839 View
ENSG00000135312 HTR1B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948307 View
ENSG00000168610 STAT3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.948297 View
ENSG00000153944 MSI2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.948251 View