ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113721 PDGFRB ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960216 View
ENSG00000097007 ABL1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960213 View
ENSG00000116016 EPAS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960171 View
ENSG00000178568 ERBB4 ENSG00000179218 CALR H. sapiens SDL Slorth 0.960007 View
ENSG00000077380 DYNC1I2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959964 View
ENSG00000100372 SLC25A17 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959923 View
ENSG00000130561 SAG ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959911 View
ENSG00000178568 ERBB4 ENSG00000186868 MAPT H. sapiens SSL Slorth 0.959897 View
ENSG00000137073 UBAP2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959857 View
ENSG00000127511 SIN3B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959678 View
ENSG00000141646 SMAD4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959618 View
ENSG00000103275 UBE2I ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959559 View
ENSG00000007908 SELE ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959552 View
ENSG00000160193 WDR4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959443 View
ENSG00000055130 CUL1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959374 View
ENSG00000070950 RAD18 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959367 View
ENSG00000132386 SERPINF1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959354 View
ENSG00000178568 ERBB4 ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.959316 View
ENSG00000166949 SMAD3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.95931 View
ENSG00000176720 BOK ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959297 View
ENSG00000105325 FZR1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959257 View
ENSG00000128052 KDR ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959257 View
ENSG00000121774 KHDRBS1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959231 View
ENSG00000103194 USP10 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.959215 View
ENSG00000178568 ERBB4 ENSG00000180176 TH H. sapiens SDL Slorth 0.959213 View
ENSG00000072163 LIMS2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.959099 View
ENSG00000095397 WHRN ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.958663 View
ENSG00000070010 UFD1L ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.958437 View
ENSG00000132155 RAF1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.958415 View
ENSG00000137693 YAP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.958403 View
ENSG00000178568 ERBB4 ENSG00000184900 SUMO3 H. sapiens SSL Slorth 0.958353 View
ENSG00000141736 ERBB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.958273 View
ENSG00000164924 YWHAZ ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.958124 View
ENSG00000139219 COL2A1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.958091 View
ENSG00000105737 GRIK5 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.958091 View
ENSG00000130766 SESN2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.957757 View
ENSG00000137673 MMP7 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.957696 View
ENSG00000123374 CDK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.95768 View
ENSG00000078747 ITCH ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.957358 View
ENSG00000178568 ERBB4 ENSG00000183207 RUVBL2 H. sapiens SSL Slorth 0.957351 View