ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113575 PPP2CA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962051 View
ENSG00000102683 SGCG ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.962008 View
ENSG00000178568 ERBB4 ENSG00000196470 SIAH1 H. sapiens SDL Slorth 0.962008 View
ENSG00000176095 IP6K1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961899 View
ENSG00000148908 RGS10 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961858 View
ENSG00000175104 TRAF6 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96177 View
ENSG00000135341 MAP3K7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961739 View
ENSG00000164924 YWHAZ ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961644 View
ENSG00000102882 MAPK3 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961597 View
ENSG00000135604 STX11 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.96158 View
ENSG00000164654 MIOS ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.96158 View
ENSG00000155465 SLC7A7 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961563 View
ENSG00000157764 BRAF ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961532 View
ENSG00000082898 XPO1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961506 View
ENSG00000119048 UBE2B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961467 View
ENSG00000100030 MAPK1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961415 View
ENSG00000111218 PRMT8 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961287 View
ENSG00000169375 SIN3A ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961193 View
ENSG00000141480 ARRB2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961191 View
ENSG00000107282 APBA1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.961151 View
ENSG00000128245 YWHAH ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961084 View
ENSG00000061273 HDAC7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96105 View
ENSG00000142208 AKT1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961042 View
ENSG00000108953 YWHAE ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.961035 View
ENSG00000097046 CDC7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960991 View
ENSG00000109670 FBXW7 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960983 View
ENSG00000123374 CDK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960981 View
ENSG00000105290 APLP1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960908 View
ENSG00000169398 PTK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960846 View
ENSG00000088367 EPB41L1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960713 View
ENSG00000096384 HSP90AB1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960694 View
ENSG00000134057 CCNB1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960594 View
ENSG00000073111 MCM2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960591 View
ENSG00000152822 GRM1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960408 View
ENSG00000110092 CCND1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960399 View
ENSG00000085449 WDFY1 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.960393 View
ENSG00000004700 RECQL ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960276 View
ENSG00000128908 INO80 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960236 View
ENSG00000132155 RAF1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960225 View
ENSG00000169083 AR ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.960221 View