ERBB4

ENSG00000178568 - H. sapiens

Pathways

Go term Description
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004716 signal transducer, downstream of receptor, with protein tyrosine kinase activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity
GO:0005154 epidermal growth factor receptor binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0042803 protein homodimerization activity
GO:0044212 transcription regulatory region DNA binding
GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity

Drugs

Drug name Description
AFATINIB Epidermal growth factor receptor erbB1 inhibitor
VANDETANIB Epidermal growth factor receptor inhibitor

Diseases

Disease Name
melanoma
gastric
NSCLC

Orthologs

Gene Organism
let-23 C. elegans
Egfr D. melanogaster

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101966 XIAP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965549 View
ENSG00000166548 TK2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.965482 View
ENSG00000177606 JUN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965462 View
ENSG00000129245 FXR2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.96529 View
ENSG00000178568 ERBB4 ENSG00000197122 SRC H. sapiens SDL Slorth 0.965279 View
ENSG00000168283 BMI1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965204 View
ENSG00000133124 IRS4 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.965189 View
ENSG00000004897 CDC27 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.965001 View
ENSG00000178568 ERBB4 ENSG00000184937 WT1 H. sapiens SDL Slorth 0.964997 View
ENSG00000005339 CREBBP ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964983 View
ENSG00000111276 CDKN1B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964957 View
ENSG00000170577 SIX2 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.96473 View
ENSG00000145386 CCNA2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964467 View
ENSG00000101146 RAE1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964393 View
ENSG00000131759 RARA ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.964333 View
ENSG00000178568 ERBB4 ENSG00000213341 CHUK H. sapiens SSL Slorth 0.964249 View
ENSG00000102996 MMP15 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.964132 View
ENSG00000149968 MMP3 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.964132 View
ENSG00000178568 ERBB4 ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.964064 View
ENSG00000136997 MYC ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.963886 View
ENSG00000010671 BTK ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.963651 View
ENSG00000012048 BRCA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.96358 View
ENSG00000113721 PDGFRB ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.963519 View
ENSG00000111540 RAB5B ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.963492 View
ENSG00000124181 PLCG1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.963294 View
ENSG00000178568 ERBB4 ENSG00000254087 LYN H. sapiens SDL Slorth 0.963193 View
ENSG00000178568 ERBB4 ENSG00000213672 NCKIPSD H. sapiens SDL Slorth 0.963123 View
ENSG00000169398 PTK2 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.963025 View
ENSG00000132383 RPA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962933 View
ENSG00000124762 CDKN1A ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.962898 View
ENSG00000170312 CDK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962845 View
ENSG00000087510 TFAP2C ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.962833 View
ENSG00000069869 NEDD4 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962712 View
ENSG00000175104 TRAF6 ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.962661 View
ENSG00000159692 CTBP1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962658 View
ENSG00000082701 GSK3B ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962645 View
ENSG00000148429 USP6NL ENSG00000178568 ERBB4 H. sapiens SDL Slorth 0.962594 View
ENSG00000100030 MAPK1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962588 View
ENSG00000101868 POLA1 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962586 View
ENSG00000064012 CASP8 ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.962271 View