ITCH - ERBB4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITCH	ENSG00000078747	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding ubiquitin-like protein transferase activity ribonucleoprotein complex binding CXCR chemokine receptor binding ubiquitin protein ligase activity	RSP5 (S. cerevisiae) wwp-1 (C. elegans) Su(dx) (D. melanogaster)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)