ERBB4 - SIAH2

SDL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)
SIAH2	ENSG00000181788	No diseases in record	No drugs in record	transcription corepressor activity ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity ubiquitin conjugating enzyme binding ubiquitin protein ligase activity	siah-1 (C. elegans) sina (D. melanogaster)