AXIN1 - ERBB4

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
AXIN1	ENSG00000103126	colorectal endometrial prostate hepatocellular carcinoma hepatoblastoma sporadic medulloblastoma	No drugs in record	signal transducer activity GTPase activator activity protein binding beta-catenin binding enzyme binding protein kinase binding receptor signaling complex scaffold activity ubiquitin protein ligase binding protein complex scaffold activity identical protein binding protein homodimerization activity SMAD binding armadillo repeat domain binding I-SMAD binding	Axn (D. melanogaster)
ERBB4	ENSG00000178568	melanoma gastric NSCLC	AFATINIB VANDETANIB	protein tyrosine kinase activity transmembrane receptor protein tyrosine kinase activity signal transducer, downstream of receptor, with protein tyrosine kinase activity Ras guanyl-nucleotide exchange factor activity epidermal growth factor receptor binding protein binding ATP binding protein homodimerization activity transcription regulatory region DNA binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity	let-23 (C. elegans) Egfr (D. melanogaster)