CBL - ERBB4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
CBL ENSG00000110395 AML
JMML
MDS

No drugs in record

phosphotyrosine residue binding
transcription factor activity, sequence-specific DNA binding
ubiquitin-protein transferase activity
signal transducer activity
calcium ion binding
protein binding
zinc ion binding
ligase activity
SH3 domain binding
receptor tyrosine kinase binding
phosphatidylinositol 3-kinase regulatory subunit binding
ephrin receptor binding
ubiquitin protein ligase activity
cadherin binding involved in cell-cell adhesion
sli-1 (C. elegans)
Cbl (D. melanogaster)
ERBB4 ENSG00000178568 melanoma
gastric
NSCLC
AFATINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
let-23 (C. elegans)
Egfr (D. melanogaster)