AKT1 - ERBB4

H. sapiens

SDL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
AKT1 ENSG00000142208 breast
colorectal
ovarian
NSCLC

No drugs in record

protein kinase activity
protein serine/threonine kinase activity
protein serine/threonine/tyrosine kinase activity
protein kinase C binding
protein binding
ATP binding
phosphatidylinositol-3,4,5-trisphosphate binding
kinase activity
enzyme binding
nitric-oxide synthase regulator activity
GTPase activating protein binding
identical protein binding
phosphatidylinositol-3,4-bisphosphate binding
protein phosphatase 2A binding
14-3-3 protein binding
phosphatidylinositol binding
SCH9 (S. cerevisiae)
YPK1 (S. cerevisiae)
YPK2 (S. cerevisiae)
akt-1 (C. elegans)
akt-2 (C. elegans)
Akt1 (D. melanogaster)
ERBB4 ENSG00000178568 melanoma
gastric
NSCLC
AFATINIB
VANDETANIB
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
signal transducer, downstream of receptor, with protein tyrosine kinase activity
Ras guanyl-nucleotide exchange factor activity
epidermal growth factor receptor binding
protein binding
ATP binding
protein homodimerization activity
transcription regulatory region DNA binding
phosphatidylinositol-4,5-bisphosphate 3-kinase activity
let-23 (C. elegans)
Egfr (D. melanogaster)