WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000079999 KEAP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.96131 View
ENSG00000149136 SSRP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961239 View
ENSG00000079335 CDC14A ENSG00000165392 WRN H. sapiens SDL Slorth 0.96121 View
ENSG00000165392 WRN ENSG00000185345 PARK2 H. sapiens SSL Slorth 0.961166 View
ENSG00000149273 RPS3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.96114 View
ENSG00000147133 TAF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961056 View
ENSG00000101665 SMAD7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.961043 View
ENSG00000075624 ACTB ENSG00000165392 WRN H. sapiens SSL Slorth 0.960985 View
ENSG00000126261 UBA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.960952 View
ENSG00000134982 APC ENSG00000165392 WRN H. sapiens SDL Slorth 0.960806 View
ENSG00000060069 CTDP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.960805 View
ENSG00000099956 SMARCB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.960769 View
ENSG00000165392 WRN ENSG00000185896 LAMP1 H. sapiens SDL Slorth 0.960692 View
ENSG00000165392 WRN ENSG00000171150 SOCS5 H. sapiens SDL Slorth 0.960692 View
ENSG00000112118 MCM3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.960584 View
ENSG00000114423 CBLB ENSG00000165392 WRN H. sapiens SSL Slorth 0.960494 View
ENSG00000127445 PIN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.960311 View
ENSG00000069869 NEDD4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.96023 View
ENSG00000165392 WRN ENSG00000253729 PRKDC H. sapiens SDL Slorth 0.959855 View
ENSG00000145734 BDP1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.959811 View
ENSG00000077380 DYNC1I2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.95979 View
ENSG00000077279 DCX ENSG00000165392 WRN H. sapiens SDL Slorth 0.959708 View
ENSG00000164654 MIOS ENSG00000165392 WRN H. sapiens SDL Slorth 0.959708 View
ENSG00000120539 MASTL ENSG00000165392 WRN H. sapiens SDL Slorth 0.959669 View
ENSG00000165392 WRN ENSG00000256223 ZNF10 H. sapiens SDL Slorth 0.959452 View
ENSG00000165392 WRN ENSG00000183684 ALYREF H. sapiens SSL Slorth 0.959372 View
ENSG00000141543 EIF4A3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.95933 View
ENSG00000023445 BIRC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.959291 View
ENSG00000111875 ASF1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.95917 View
ENSG00000152601 MBNL1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.959164 View
ENSG00000113721 PDGFRB ENSG00000165392 WRN H. sapiens SSL Slorth 0.959146 View
ENSG00000165392 WRN ENSG00000172531 PPP1CA H. sapiens SSL Slorth 0.95913 View
ENSG00000101266 CSNK2A1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.959075 View
ENSG00000146648 EGFR ENSG00000165392 WRN H. sapiens SDL Slorth 0.958963 View
ENSG00000080815 PSEN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.958826 View
ENSG00000136997 MYC ENSG00000165392 WRN H. sapiens SDL Slorth 0.958742 View
ENSG00000078140 UBE2K ENSG00000165392 WRN H. sapiens SSL Slorth 0.958697 View
ENSG00000165392 WRN ENSG00000253729 PRKDC H. sapiens SSL Slorth 0.958693 View
ENSG00000110330 BIRC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.958609 View
ENSG00000165392 WRN ENSG00000196419 XRCC6 H. sapiens SSL Slorth 0.958503 View