WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000101266 CSNK2A1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.955224 View
ENSG00000100320 RBFOX2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.955183 View
ENSG00000077935 SMC1B ENSG00000165392 WRN H. sapiens SDL Slorth 0.95518 View
ENSG00000021574 SPAST ENSG00000165392 WRN H. sapiens SDL Slorth 0.95518 View
ENSG00000165392 WRN ENSG00000175792 RUVBL1 H. sapiens SSL Slorth 0.955173 View
ENSG00000100030 MAPK1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.955128 View
ENSG00000106462 EZH2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.955101 View
ENSG00000165392 WRN ENSG00000180900 SCRIB H. sapiens SDL Slorth 0.954797 View
ENSG00000134308 YWHAQ ENSG00000165392 WRN H. sapiens SSL Slorth 0.954796 View
ENSG00000165392 WRN ENSG00000168496 FEN1 H. sapiens SSL Slorth 0.954737 View
ENSG00000114062 UBE3A ENSG00000165392 WRN H. sapiens SSL Slorth 0.954522 View
ENSG00000150753 CCT5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.954097 View
ENSG00000053900 ANAPC4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953999 View
ENSG00000135624 CCT7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.95393 View
ENSG00000101412 E2F1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953915 View
ENSG00000118046 STK11 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953861 View
ENSG00000129245 FXR2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.953854 View
ENSG00000165392 WRN ENSG00000198353 HOXC4 H. sapiens SDL Slorth 0.953835 View
ENSG00000084676 NCOA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953693 View
ENSG00000151247 EIF4E ENSG00000165392 WRN H. sapiens SSL Slorth 0.95349 View
ENSG00000153147 SMARCA5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953407 View
ENSG00000154997 SEPT14 ENSG00000165392 WRN H. sapiens SDL Slorth 0.953379 View
ENSG00000082146 STRADB ENSG00000165392 WRN H. sapiens SDL Slorth 0.953367 View
ENSG00000132646 PCNA ENSG00000165392 WRN H. sapiens SSL Slorth 0.953274 View
ENSG00000140464 PML ENSG00000165392 WRN H. sapiens SDL Slorth 0.953178 View
ENSG00000136450 SRSF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.953067 View
ENSG00000165392 WRN ENSG00000198793 MTOR H. sapiens SSL Slorth 0.953065 View
ENSG00000165392 WRN ENSG00000166200 COPS2 H. sapiens SSL Slorth 0.952987 View
ENSG00000165392 WRN ENSG00000180176 TH H. sapiens SDL Slorth 0.952863 View
ENSG00000070831 CDC42 ENSG00000165392 WRN H. sapiens SSL Slorth 0.952849 View
ENSG00000126561 STAT5A ENSG00000165392 WRN H. sapiens SSL Slorth 0.952772 View
ENSG00000073111 MCM2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.952745 View
ENSG00000074319 TSG101 ENSG00000165392 WRN H. sapiens SSL Slorth 0.952525 View
ENSG00000099804 CDC34 ENSG00000165392 WRN H. sapiens SSL Slorth 0.952498 View
ENSG00000122406 RPL5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.952419 View
ENSG00000102978 POLR2C ENSG00000165392 WRN H. sapiens SSL Slorth 0.95241 View
ENSG00000130939 UBE4B ENSG00000165392 WRN H. sapiens SSL Slorth 0.952386 View
ENSG00000129152 MYOD1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.952291 View
ENSG00000165392 WRN ENSG00000283094 PTEN H. sapiens SSL Slorth 0.952105 View
ENSG00000112592 TBP ENSG00000165392 WRN H. sapiens SDL Slorth 0.95205 View