WRN - MTOR

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
WRN ENSG00000165392 osteosarcoma
meningioma
other tumour types

No drugs in record

magnesium ion binding
Y-form DNA binding
bubble DNA binding
DNA binding
DNA helicase activity
chromatin binding
ATP-dependent DNA helicase activity
helicase activity
exonuclease activity
protein binding
ATP binding
3'-5' exonuclease activity
four-way junction helicase activity
ATPase activity
manganese ion binding
protein complex binding
protein homodimerization activity
3'-5' DNA helicase activity
ATP-dependent 3'-5' DNA helicase activity
G-quadruplex DNA binding
SGS1 (S. cerevisiae)
wrn-1 (C. elegans)
MTOR ENSG00000198793 endometrial carcinoma
head and neck
clear cell renal cell carcinoma
anaplastic thyroid cancer
urothelial cell carcinoma
central nervous system tumours
testicular germ cell tumours and other tumour types

No drugs in record

RNA polymerase III type 1 promoter DNA binding
RNA polymerase III type 2 promoter DNA binding
RNA polymerase III type 3 promoter DNA binding
TFIIIC-class transcription factor binding
protein kinase activity
protein serine/threonine kinase activity
protein binding
ATP binding
kinase activity
protein kinase binding
protein domain specific binding
ribosome binding
phosphoprotein binding
ribonucleoprotein complex binding
chromatin DNA binding
nucleocytoplasmic transporter activity
TOR2 (S. cerevisiae)
Tor (D. melanogaster)