WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000063245 EPN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758505 View
ENSG00000165392 WRN ENSG00000171848 RRM2 H. sapiens SSL Slorth 0.758218 View
ENSG00000028528 SNX1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758184 View
ENSG00000079805 DNM2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758142 View
ENSG00000133226 SRRM1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758056 View
ENSG00000109189 USP46 ENSG00000165392 WRN H. sapiens SSL Slorth 0.757918 View
ENSG00000127564 PKMYT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.757784 View
ENSG00000065000 AP3D1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.756159 View
ENSG00000165392 WRN ENSG00000167965 MLST8 H. sapiens SSL Slorth 0.756082 View
ENSG00000165392 WRN ENSG00000179262 RAD23A H. sapiens SSL Slorth 0.755991 View
ENSG00000115306 SPTBN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.755954 View
ENSG00000165392 WRN ENSG00000187741 FANCA H. sapiens SSL Slorth 0.755792 View
ENSG00000165392 WRN ENSG00000173757 STAT5B H. sapiens SSL Slorth 0.755629 View
ENSG00000165392 WRN ENSG00000183495 EP400 H. sapiens SSL Slorth 0.755415 View
ENSG00000165392 WRN ENSG00000169032 MAP2K1 H. sapiens SSL Slorth 0.755256 View
ENSG00000047410 TPR ENSG00000165392 WRN H. sapiens SSL Slorth 0.755183 View
ENSG00000151532 VTI1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.754784 View
ENSG00000136271 DDX56 ENSG00000165392 WRN H. sapiens SSL Slorth 0.754732 View
ENSG00000086589 RBM22 ENSG00000165392 WRN H. sapiens SSL Slorth 0.754215 View
ENSG00000003400 CASP10 ENSG00000165392 WRN H. sapiens SSL Slorth 0.753641 View
ENSG00000134597 RBMX2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.751532 View
ENSG00000143106 PSMA5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.751271 View
ENSG00000105402 NAPA ENSG00000165392 WRN H. sapiens SSL Slorth 0.751042 View
ENSG00000135766 EGLN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.750144 View
ENSG00000165392 WRN ENSG00000170473 PYM1 H. sapiens SSL Slorth 0.750109 View
ENSG00000104517 UBR5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.750085 View