WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000017797 RALBP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.767522 View
ENSG00000165392 WRN ENSG00000198677 TTC37 H. sapiens SSL Slorth 0.767505 View
ENSG00000165392 WRN ENSG00000198909 MAP3K3 H. sapiens SSL Slorth 0.767202 View
ENSG00000164867 NOS3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.767159 View
ENSG00000144848 ATG3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.767015 View
ENSG00000165392 WRN ENSG00000197442 MAP3K5 H. sapiens SSL Slorth 0.767002 View
ENSG00000115286 NDUFS7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.766736 View
ENSG00000136100 VPS36 ENSG00000165392 WRN H. sapiens SSL Slorth 0.766462 View
ENSG00000135503 ACVR1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.766413 View
ENSG00000156603 MED19 ENSG00000165392 WRN H. sapiens SSL Slorth 0.766287 View
ENSG00000105248 CCDC94 ENSG00000165392 WRN H. sapiens SSL Slorth 0.765582 View
ENSG00000165392 WRN ENSG00000175595 ERCC4 H. sapiens SSL Slorth 0.765434 View
ENSG00000136273 HUS1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.765417 View
ENSG00000165392 WRN ENSG00000172845 SP3 H. sapiens SSL Slorth 0.765325 View
ENSG00000122367 LDB3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.765264 View
ENSG00000164022 AIMP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.764786 View
ENSG00000113282 CLINT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.764771 View
ENSG00000115946 PNO1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.764388 View
ENSG00000165392 WRN ENSG00000198522 GPN1 H. sapiens SSL Slorth 0.764274 View
ENSG00000089685 BIRC5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.764256 View
ENSG00000112742 TTK ENSG00000165392 WRN H. sapiens SSL Slorth 0.764047 View
ENSG00000163029 SMC6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.763503 View
ENSG00000143933 CALM2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.763444 View
ENSG00000009335 UBE3C ENSG00000165392 WRN H. sapiens SSL Slorth 0.762907 View
ENSG00000133026 MYH10 ENSG00000165392 WRN H. sapiens SSL Slorth 0.762633 View
ENSG00000164754 RAD21 ENSG00000165392 WRN H. sapiens SSL Slorth 0.762495 View
ENSG00000068654 POLR1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.761676 View
ENSG00000141867 BRD4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.761672 View
ENSG00000076555 ACACB ENSG00000165392 WRN H. sapiens SSL Slorth 0.761559 View
ENSG00000129084 PSMA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.761017 View
ENSG00000130522 JUND ENSG00000165392 WRN H. sapiens SSL Slorth 0.760747 View
ENSG00000122218 COPA ENSG00000165392 WRN H. sapiens SSL Slorth 0.760471 View
ENSG00000159259 CHAF1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.760404 View
ENSG00000122545 SEPT7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.760318 View
ENSG00000115145 STAM2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.75979 View
ENSG00000165392 WRN ENSG00000198836 OPA1 H. sapiens SSL Slorth 0.759115 View
ENSG00000112685 EXOC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758965 View
ENSG00000143761 ARF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.75894 View
ENSG00000153201 RANBP2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.758792 View
ENSG00000165392 WRN ENSG00000204843 DCTN1 H. sapiens SSL Slorth 0.758788 View