WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000099381 SETD1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.838042 View
ENSG00000108106 UBE2S ENSG00000165392 WRN H. sapiens SSL Slorth 0.837994 View
ENSG00000147573 TRIM55 ENSG00000165392 WRN H. sapiens SSL Slorth 0.83783 View
ENSG00000106636 YKT6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.837366 View
ENSG00000165392 WRN ENSG00000169750 RAC3 H. sapiens SSL Slorth 0.837244 View
ENSG00000133627 ACTR3B ENSG00000165392 WRN H. sapiens SSL Slorth 0.835265 View
ENSG00000165392 WRN ENSG00000188021 UBQLN2 H. sapiens SSL Slorth 0.83514 View
ENSG00000118971 CCND2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.835026 View
ENSG00000080608 PUM3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.834924 View
ENSG00000138385 SSB ENSG00000165392 WRN H. sapiens SSL Slorth 0.834584 View
ENSG00000141367 CLTC ENSG00000165392 WRN H. sapiens SSL Slorth 0.834234 View
ENSG00000101460 MAP1LC3A ENSG00000165392 WRN H. sapiens SSL Slorth 0.834196 View
ENSG00000102554 KLF5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.834133 View
ENSG00000106245 BUD31 ENSG00000165392 WRN H. sapiens SSL Slorth 0.832678 View
ENSG00000134070 IRAK2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.832416 View
ENSG00000103549 RNF40 ENSG00000165392 WRN H. sapiens SSL Slorth 0.832347 View
ENSG00000101361 NOP56 ENSG00000165392 WRN H. sapiens SSL Slorth 0.832322 View
ENSG00000089737 DDX24 ENSG00000165392 WRN H. sapiens SSL Slorth 0.832218 View
ENSG00000114126 TFDP2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.831688 View
ENSG00000129559 NEDD8 ENSG00000165392 WRN H. sapiens SSL Slorth 0.831579 View
ENSG00000077150 NFKB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.831525 View
ENSG00000165392 WRN ENSG00000215301 DDX3X H. sapiens SSL Slorth 0.830377 View
ENSG00000145907 G3BP1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.829951 View
ENSG00000116062 MSH6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.829737 View
ENSG00000049246 PER3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.829583 View
ENSG00000034152 MAP2K3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.829087 View
ENSG00000152795 HNRNPDL ENSG00000165392 WRN H. sapiens SSL Slorth 0.828671 View
ENSG00000057657 PRDM1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.828585 View
ENSG00000151461 UPF2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.827873 View
ENSG00000104885 DOT1L ENSG00000165392 WRN H. sapiens SSL Slorth 0.827403 View
ENSG00000142168 SOD1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.826574 View
ENSG00000112578 BYSL ENSG00000165392 WRN H. sapiens SSL Slorth 0.826489 View
ENSG00000049541 RFC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.824846 View
ENSG00000164934 DCAF13 ENSG00000165392 WRN H. sapiens SSL Slorth 0.824299 View
ENSG00000100722 ZC3H14 ENSG00000165392 WRN H. sapiens SSL Slorth 0.823164 View
ENSG00000163938 GNL3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.82313 View
ENSG00000149792 MRPL49 ENSG00000165392 WRN H. sapiens SSL Slorth 0.822993 View
ENSG00000142453 CARM1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.822099 View
ENSG00000125630 POLR1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.821562 View
ENSG00000160789 LMNA ENSG00000165392 WRN H. sapiens SSL Slorth 0.821355 View