WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000007168 PAFAH1B1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.885272 View
ENSG00000280548 FBL ENSG00000165392 WRN H. sapiens SSL Slorth 0.88497 View
ENSG00000115464 USP34 ENSG00000165392 WRN H. sapiens SSL Slorth 0.88471 View
ENSG00000130725 UBE2M ENSG00000165392 WRN H. sapiens SSL Slorth 0.884649 View
ENSG00000147162 OGT ENSG00000165392 WRN H. sapiens SSL Slorth 0.884483 View
ENSG00000070756 PABPC1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.884361 View
ENSG00000132612 VPS4A ENSG00000165392 WRN H. sapiens SSL Slorth 0.8843 View
ENSG00000125107 CNOT1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.883582 View
ENSG00000102981 PARD6A ENSG00000165392 WRN H. sapiens SSL Slorth 0.883527 View
ENSG00000143801 PSEN2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.883381 View
ENSG00000147669 POLR2K ENSG00000165392 WRN H. sapiens SSL Slorth 0.883212 View
ENSG00000100083 GGA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.88312 View
ENSG00000105974 CAV1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.882953 View
ENSG00000054116 TRAPPC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.882599 View
ENSG00000157020 SEC13 ENSG00000165392 WRN H. sapiens SSL Slorth 0.882517 View
ENSG00000066654 THUMPD1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.88194 View
ENSG00000084774 CAD ENSG00000165392 WRN H. sapiens SSL Slorth 0.881764 View
ENSG00000165392 WRN ENSG00000196305 IARS H. sapiens SSL Slorth 0.881634 View
ENSG00000113141 IK ENSG00000165392 WRN H. sapiens SSL Slorth 0.881632 View
ENSG00000165392 WRN ENSG00000178568 ERBB4 H. sapiens SSL Slorth 0.881611 View
ENSG00000101161 PRPF6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.880891 View
ENSG00000158169 FANCC ENSG00000165392 WRN H. sapiens SSL Slorth 0.880599 View
ENSG00000108055 SMC3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.880463 View
ENSG00000104695 PPP2CB ENSG00000165392 WRN H. sapiens SSL Slorth 0.88038 View
ENSG00000119707 RBM25 ENSG00000165392 WRN H. sapiens SSL Slorth 0.880334 View
ENSG00000100201 DDX17 ENSG00000165392 WRN H. sapiens SSL Slorth 0.880287 View
ENSG00000092531 SNAP23 ENSG00000165392 WRN H. sapiens SSL Slorth 0.880149 View
ENSG00000165392 WRN ENSG00000196235 SUPT5H H. sapiens SSL Slorth 0.880018 View
ENSG00000137076 TLN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.879534 View
ENSG00000092820 EZR ENSG00000165392 WRN H. sapiens SSL Slorth 0.87948 View
ENSG00000123358 NR4A1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.879222 View
ENSG00000156304 SCAF4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.879189 View
ENSG00000065548 ZC3H15 ENSG00000165392 WRN H. sapiens SSL Slorth 0.878901 View
ENSG00000103363 TCEB2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.878857 View
ENSG00000141384 TAF4B ENSG00000165392 WRN H. sapiens SSL Slorth 0.878729 View
ENSG00000100351 GRAP2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.878383 View
ENSG00000165392 WRN ENSG00000172053 QARS H. sapiens SSL Slorth 0.878287 View
ENSG00000122692 SMU1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.877976 View
ENSG00000139618 BRCA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.877655 View
ENSG00000013503 POLR3B ENSG00000165392 WRN H. sapiens SSL Slorth 0.877041 View