WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000113812 ACTR8 ENSG00000165392 WRN H. sapiens SSL Slorth 0.896299 View
ENSG00000119718 EIF2B2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.896195 View
ENSG00000156970 BUB1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.896117 View
ENSG00000072110 ACTN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.89594 View
ENSG00000048052 HDAC9 ENSG00000165392 WRN H. sapiens SSL Slorth 0.895798 View
ENSG00000165392 WRN ENSG00000175197 DDIT3 H. sapiens SSL Slorth 0.895787 View
ENSG00000165392 WRN ENSG00000183431 SF3A3 H. sapiens SSL Slorth 0.895697 View
ENSG00000088986 DYNLL1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.894986 View
ENSG00000165392 WRN ENSG00000198554 WDHD1 H. sapiens SSL Slorth 0.894804 View
ENSG00000076984 MAP2K7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.894788 View
ENSG00000106211 HSPB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.894622 View
ENSG00000122512 PMS2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.89458 View
ENSG00000138668 HNRNPD ENSG00000165392 WRN H. sapiens SSL Slorth 0.894489 View
ENSG00000165392 WRN ENSG00000172534 HCFC1 H. sapiens SSL Slorth 0.894053 View
ENSG00000127955 GNAI1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.893567 View
ENSG00000122257 RBBP6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.893444 View
ENSG00000134480 CCNH ENSG00000165392 WRN H. sapiens SSL Slorth 0.893432 View
ENSG00000144566 RAB5A ENSG00000165392 WRN H. sapiens SSL Slorth 0.892156 View
ENSG00000137834 SMAD6 ENSG00000165392 WRN H. sapiens SSL Slorth 0.892064 View
ENSG00000080986 NDC80 ENSG00000165392 WRN H. sapiens SSL Slorth 0.892034 View
ENSG00000118503 TNFAIP3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.89161 View
ENSG00000111581 NUP107 ENSG00000165392 WRN H. sapiens SSL Slorth 0.891552 View
ENSG00000128591 FLNC ENSG00000165392 WRN H. sapiens SSL Slorth 0.891324 View
ENSG00000049618 ARID1B ENSG00000165392 WRN H. sapiens SSL Slorth 0.890371 View
ENSG00000109062 SLC9A3R1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.890276 View
ENSG00000133794 ARNTL ENSG00000165392 WRN H. sapiens SSL Slorth 0.890234 View
ENSG00000165392 WRN ENSG00000196470 SIAH1 H. sapiens SSL Slorth 0.890214 View
ENSG00000044574 HSPA5 ENSG00000165392 WRN H. sapiens SSL Slorth 0.889977 View
ENSG00000141552 ANAPC11 ENSG00000165392 WRN H. sapiens SSL Slorth 0.889603 View
ENSG00000047932 GOPC ENSG00000165392 WRN H. sapiens SSL Slorth 0.889471 View
ENSG00000137309 HMGA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.888926 View
ENSG00000129083 COPB1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.887832 View
ENSG00000083520 DIS3 ENSG00000165392 WRN H. sapiens SSL Slorth 0.887572 View
ENSG00000096063 SRPK1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.886666 View
ENSG00000099995 SF3A1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.886629 View
ENSG00000165392 WRN ENSG00000169967 MAP3K2 H. sapiens SSL Slorth 0.886611 View
ENSG00000163466 ARPC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.886497 View
ENSG00000137815 RTF1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.8859 View
ENSG00000136527 TRA2B ENSG00000165392 WRN H. sapiens SSL Slorth 0.885833 View
ENSG00000133895 MEN1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.885379 View