WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000008853 RHOBTB2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910034 View
ENSG00000133124 IRS4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.909816 View
ENSG00000130726 TRIM28 ENSG00000165392 WRN H. sapiens SDL Slorth 0.909712 View
ENSG00000113575 PPP2CA ENSG00000165392 WRN H. sapiens SSL Slorth 0.909701 View
ENSG00000124232 RBPJL ENSG00000165392 WRN H. sapiens SDL Slorth 0.909701 View
ENSG00000130766 SESN2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.909685 View
ENSG00000087095 NLK ENSG00000165392 WRN H. sapiens SSL Slorth 0.909676 View
ENSG00000130826 DKC1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.909611 View
ENSG00000143252 SDHC ENSG00000165392 WRN H. sapiens SDL Slorth 0.90931 View
ENSG00000135776 ABCB10 ENSG00000165392 WRN H. sapiens SDL Slorth 0.909221 View
ENSG00000106628 POLD2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.909147 View
ENSG00000149781 FERMT3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.9091 View
ENSG00000107929 LARP4B ENSG00000165392 WRN H. sapiens SDL Slorth 0.909018 View
ENSG00000163517 HDAC11 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908959 View
ENSG00000165392 WRN ENSG00000183735 TBK1 H. sapiens SSL Slorth 0.908922 View
ENSG00000104140 RHOV ENSG00000165392 WRN H. sapiens SDL Slorth 0.908825 View
ENSG00000130751 NPAS1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908825 View
ENSG00000143847 PPFIA4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908825 View
ENSG00000112246 SIM1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908825 View
ENSG00000151746 BICD1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908825 View
ENSG00000139613 SMARCC2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.908756 View
ENSG00000135521 LTV1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.908709 View
ENSG00000110092 CCND1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908694 View
ENSG00000164284 GRPEL2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908659 View
ENSG00000100297 MCM5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.908585 View
ENSG00000138663 COPS4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.908577 View
ENSG00000126785 RHOJ ENSG00000165392 WRN H. sapiens SDL Slorth 0.90856 View
ENSG00000165392 WRN ENSG00000203879 GDI1 H. sapiens SDL Slorth 0.90838 View
ENSG00000164362 TERT ENSG00000165392 WRN H. sapiens SSL Slorth 0.908307 View
ENSG00000007264 MATK ENSG00000165392 WRN H. sapiens SDL Slorth 0.90794 View
ENSG00000115592 PRKAG3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907819 View
ENSG00000159352 PSMD4 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907768 View
ENSG00000116288 PARK7 ENSG00000165392 WRN H. sapiens SSL Slorth 0.907754 View
ENSG00000154237 LRRK1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907734 View
ENSG00000136750 GAD2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907364 View
ENSG00000165392 WRN ENSG00000198286 CARD11 H. sapiens SDL Slorth 0.907283 View
ENSG00000165125 TRPV6 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907195 View
ENSG00000165392 WRN ENSG00000245848 CEBPA H. sapiens SSL Slorth 0.907191 View
ENSG00000104129 DNAJC17 ENSG00000165392 WRN H. sapiens SDL Slorth 0.907015 View
ENSG00000071242 RPS6KA2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.906979 View