WRN

ENSG00000165392 - H. sapiens

Pathways

Go term Description
GO:0000287 magnesium ion binding
GO:0000403 Y-form DNA binding
GO:0000405 bubble DNA binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003682 chromatin binding
GO:0004003 ATP-dependent DNA helicase activity
GO:0004386 helicase activity
GO:0004527 exonuclease activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008408 3'-5' exonuclease activity
GO:0009378 four-way junction helicase activity
GO:0016887 ATPase activity
GO:0030145 manganese ion binding
GO:0032403 protein complex binding
GO:0042803 protein homodimerization activity
GO:0043138 3'-5' DNA helicase activity
GO:0043140 ATP-dependent 3'-5' DNA helicase activity
GO:0051880 G-quadruplex DNA binding

Drugs

No drugs in record

Diseases

Disease Name
osteosarcoma
meningioma
other tumour types

Orthologs

Gene Organism
SGS1 S. cerevisiae
wrn-1 C. elegans

Related Interactions

Gene ID A Gene Name A Gene ID B Gene Symbol B Organism Source Score?
ENSG00000165392 WRN ENSG00000175203 DCTN2 H. sapiens SDL Slorth 0.911899 View
ENSG00000165392 WRN ENSG00000170836 PPM1D H. sapiens SDL Slorth 0.911887 View
ENSG00000159216 RUNX1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.911856 View
ENSG00000160145 KALRN ENSG00000165392 WRN H. sapiens SDL Slorth 0.911679 View
ENSG00000165392 WRN ENSG00000173846 PLK3 H. sapiens SDL Slorth 0.911636 View
ENSG00000147065 MSN ENSG00000165392 WRN H. sapiens SSL Slorth 0.911498 View
ENSG00000101134 DOK5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.911469 View
ENSG00000163904 SENP2 ENSG00000165392 WRN H. sapiens SSL Slorth 0.911185 View
ENSG00000115085 ZAP70 ENSG00000165392 WRN H. sapiens SSL Slorth 0.911105 View
ENSG00000165392 WRN ENSG00000168090 COPS6 H. sapiens SSL Slorth 0.911054 View
ENSG00000101665 SMAD7 ENSG00000165392 WRN H. sapiens SDL Slorth 0.911036 View
ENSG00000106689 LHX2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910975 View
ENSG00000136944 LMX1B ENSG00000165392 WRN H. sapiens SDL Slorth 0.910975 View
ENSG00000157216 SSBP3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910975 View
ENSG00000130985 UBA1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.910973 View
ENSG00000111540 RAB5B ENSG00000165392 WRN H. sapiens SDL Slorth 0.910966 View
ENSG00000064489 BORCS8-MEF2B ENSG00000165392 WRN H. sapiens SDL Slorth 0.910947 View
ENSG00000163064 EN1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910947 View
ENSG00000116350 SRSF4 ENSG00000165392 WRN H. sapiens SSL Slorth 0.910923 View
ENSG00000070476 ZXDC ENSG00000165392 WRN H. sapiens SDL Slorth 0.910793 View
ENSG00000145506 NKD2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910793 View
ENSG00000165392 WRN ENSG00000171223 JUNB H. sapiens SSL Slorth 0.910791 View
ENSG00000127445 PIN1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910676 View
ENSG00000085185 BCORL1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000115616 SLC9A2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000138594 TMOD3 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000153132 CLGN ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000139219 COL2A1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000105737 GRIK5 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000100228 RAB36 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000140199 SLC12A6 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000163394 CCKAR ENSG00000165392 WRN H. sapiens SDL Slorth 0.910606 View
ENSG00000074219 TEAD2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910599 View
ENSG00000120738 EGR1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.91054 View
ENSG00000116473 RAP1A ENSG00000165392 WRN H. sapiens SSL Slorth 0.910399 View
ENSG00000117707 PROX1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910386 View
ENSG00000080839 RBL1 ENSG00000165392 WRN H. sapiens SSL Slorth 0.910238 View
ENSG00000108830 RND2 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910054 View
ENSG00000104852 SNRNP70 ENSG00000165392 WRN H. sapiens SSL Slorth 0.910042 View
ENSG00000072422 RHOBTB1 ENSG00000165392 WRN H. sapiens SDL Slorth 0.910034 View